By road
Sambalpur is well served by road for both commercial and public transport. National Highway 53 / Economic Corridor 1 (EC1) runs through the city and forms part of Asian Highway AH46, the Mumbai–Kolkata corridor.
The city is well connected to Rourkela, Raipur and Bhubaneswar. Driving from further afield, routes run via NH48 and NH53 with convenient stops at Pune, Raipur, Nagpur, Ranchi, Lucknow and Agra.